Structure Activity Relationships in Alkylammonium C12-Gemini Surfactants Used as Dermal Permeation Enhancers

Dicationic Alkylammonium Bromide Gemini Surfactants. Membrane Perturbation and Skin Irritation

Dicationic alkylammonium bromide gemini surfactants represent a class of amphiphiles potentially effective as skin permeation enhancers. However, only a limited number of studies has been dedicated to the evaluation of the respective cytotoxicity, and none directed to skin irritation endpoints. Supported on a cell viability study, the cytotoxicity of gemini surfactants of variable tail and spac...

Gemini alkylammonium salts as biodeterioration inhibitors.

To protect materials against biodeterioration, physical, biological or chemical methods can be used. Chemical inhibitors of biodeterioration are the most common and effective. A new class of chemical inhibitors-gemini alkylammonium salts-shows excellent biocidal properties and good ecological profile. These compounds can be applied as biodeterioration inhibitors in a wide variety of materials.

Carbohydrate-Based Surfactants: Structure-Activity Relationships

Carbohydrate-based surfactants (CBS) are, today, among the most important classes of amphiphilic compounds (Dembintsky, 2004; Queneau et al, 2008; Ruiz, 2009). Their structure is the result of the saccharide and lipid combination, naturally biosynthesized within living cells, or synthetically prepared by sequential reactions using carbohydrate and fatty materials, through one or several bonds. ...

Urea-based gemini surfactants: Synthesis, aggregation behaviour and biological activity

a Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, Bratislava, SK-83232 Slovakia b Institute for Solid State Physics and Optics, Wigner Research Centre for Physics, Hungarian Academy of Sciences, H-1121 Budapest, Hungary c Key Laboratory of Neutron Physics and Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, Mianyang 621999, Chin...

Novel Peptide-Modified Gemini Surfactants as Gene Carriers: Structure Activity Relationship, Physiochemical Characterizations and Mass Spectrometric Dissociation Behaviour